Eicosanoids in the Cardiovascular and Renal Systems (Advances in Eicosanoid Research)


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A glance at those books illustrates the progress that has been made since then. The thromboxanes were mentioned twice first publication and prostacyclin not once first publication ; leukotrienes were only on the horizon. The amazing generation of research data in the last years has given new, broad insights into many areas, including asthma, inflammation, renaL cardiovascular and gastrointestinal diseases and in reproduction, and has led in some instances to real clinical benefit.

This series, Advances in Eicosanoid Research, reflects the current understanding of prostaglandins, thromboxanes and leukotrienes. The aim is to provide an introductory background to each topic and the most up-to-date information available. Although each book stands alone, the eicosanoids cut across many boundaries in their basic actions; selected chapters from each book in the series will provide illuminating and productive information for all readers which will advance their education and research. In the production of this series, I must acknowledge with pleasure my collaboration with editors and authors and the patient endeavours of Dr Michael Brewis and the staff at MTP Press.

This volume can be recommended as a good reference book for medical students and graduates of medical school. Visit Seller's Storefront. Box Hopeland, PA books mountainviewbooks. Orders usually ship within 2 business days. Shipping costs are based on books weighing 2. List this Seller's Books. Payment Methods accepted by seller. AbeBooks Bookseller Since: 11 August Microsomal prostaglandin E synthase is regulated by proinflammatory cytokines and glucocorticoids in primary rheumatoid synovial cells. Nah, S.

Kusunoki, N. Adiponectin stimulates prostaglandin E 2 production in rheumatoid synovial fibroblasts. Jungel, A. Microparticles stimulate the synthesis of prostaglandin E 2 via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. Tong, M. Reciprocal regulation of cyclooxygenase-2 and hydroxyprostaglandin dehydrogenase expression in A human lung adenocarcinoma cells. Carcinogenesis 27 , — Newton, R. Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA.

Dolhain, R. Methotrexate reduces inflammatory cell numbers, expression of monokines and of adhesion molecules in synovial tissue of patients with rheumatoid arthritis. Mello, S. Methotrexate as a preferential cyclooxygenase 2 inhibitor in whole blood of patients with rheumatoid arthritis. Rheumatology Oxford 39 , — Vergne, P. Methotrexate and cyclooxygenase metabolism in cultured human rheumatoid synoviocytes.


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Seitz, M. In vitro modulation of cytokine, cytokine inhibitor, and prostaglandin E release from blood mononuclear cells and synovial fibroblasts by antirheumatic drugs. Tracey, D. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Catrina, A.

Cyclooxygenase Deficiency

Evidence that anti-tumor necrosis factor therapy with both etanercept and infliximab induces apoptosis in macrophages, but not lymphocytes, in rheumatoid arthritis joints: extended report. Thurlings, R. Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response. Klickstein, L. Lipoxygenation of arachidonic acid as a source of polymorphonuclear leukocyte chemotactic factors in synovial fluid and tissue in rheumatoid arthritis and spondyloarthritis.

Davidson, E. Leukotriene B4, a mediator of inflammation present in synovial fluid in rheumatoid arthritis. Elmgreen, J.

Eicosanoids in the Cardiovascular and Renal Systems

Enhanced capacity for release of leucotriene B4 by neutrophils in rheumatoid arthritis. Ahmadzadeh, N.

Relationship between leukotriene B4 and immunological parameters in rheumatoid synovial fluids. Inflammation 15 , — Koshihara, Y. Measurement of sulfidopeptide leukotrienes and their metabolism in human synovial fluid of patients with rheumatoid arthritis. Fatty Acids 32 , — Xu, S. Chen, M.

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Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis. Chen, H. Fatty Acids 80 , — Garcia, C. Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo.